A glimmer of hope for kidney patients.. here are the details

15 August, 2022
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A glimmer of hope for kidney patients.. here are the details
In a move that will constitute a real revolution in the world of organ transplantation, scientists succeeded in changing the blood type of three kidneys with the aim of transplanting them while overcoming the condition that some blood types must be matched between the donor and the patient.

It is not possible to transplant a kidney from a person with blood type A to someone with blood type B, nor vice versa, but changing the blood type to a general donor will allow for more transplants.

According to the British "Sky News" network, researchers from the University of Cambridge used the normal thermal perfusion machine, a device connected to a human kidney that passes oxygenated blood through the organ, to better preserve it and use it in the future.
The blood is washed with an enzyme that removes the marks of the type that line the blood vessels in the kidneys, which leads to converting the organ to the general donor type O, and thus the ability to transplant it to anyone, regardless of their blood type.

Ayesha Edmonson, a mother of two from Bury, Manchester, who was diagnosed with stage 3 chronic kidney disease in 1998 when she was pregnant with her first child, described the news as wonderful. "It gives us hope that thousands of lives will be saved around the world," she added.

According to Serena Macmillan, a doctoral student at the University of Cambridge, the achievement “can impact the lives of many people. Our confidence was boosted after we applied the enzyme to a piece of human kidney tissue and quickly saw that the antigens had been removed. After that, we knew the process was possible, and we just had to scale up the experiment to apply the enzyme to full-size human kidneys.”

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